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MONTANIDE™ ISA
Montanide ISA are ready to use adjuvants which allow the manufacturer of different type of emulsions. Water in oil, oil in water, or water in oil in water. They can be based on mineral oil, non mineral oil or a mix of them.
ADJUVANT SELECTION
Adjuvant selection is a key criteria for oil adjuvated vaccine. Following factors need to be considered.
- Type of species/ Animals. (Cattle/Avian/Fish/swine/ Horses/Pets)
- Disease/Antigen
- Immunity (Long term/Short term)
- Route of administration ( Mucosal Coral, Nasal)/ Intra Muscular/ Intra Venous)
- Type of Vaccine ( Bacterial/Viral/Parasites)
Above parameters play a key role to enhance efficacy of vaccine with no or acceptable local reaction.
We work closely with all our customers and can extend best possible support from selecting an adjuvant to scaling up of vaccine production.
MONTANIDE RANGE OF ADJUVANTS
Ready to use Adjuvant
- No formulation optimization required
- Excellent reproducibility of adjuvant performance
- Fixed antigen : adjuvant Ratio
- Montanide are excellent for multivalent vaccine
Excellent Efficacy and Safety of Vaccines
- Different blend of oils to optimize the efficacy-safety balance.
- Quality of Adjuvant (Manufactured under GMP-Like conditions.)
- More than 20 years experience.
Technical Support
- SEPPIC expertise in emulsion.
- Adjuvant optimization : Tailor made adjuvant
- Dedicated emulsification protocol.
- Technical assistance for scaling up to production. (Process, Choice of equipment, Selection of adjuvant).
Veterinary Adjuvant
| ADJUVANT FOR VETERINARY APPLICATION | |||
|---|---|---|---|
| PRODUCTS | TYPE OF FORMULATION | RATIO AQUEOUS PHASE / OIL PHASE | TYPE OF OIL |
MONTANIDE ISA 25 VG |
Water / Oil |
25/75 |
Mineral oil - USP |
MONTANIDE ISA 28 VG |
Water / Oil |
25/75 |
Non Mineral oil - USP |
MONTANIDE ISA 35 VG |
Water / Oil |
25/75 |
Mineral oil - USP |
MONTANIDE ISA 50 VG |
Water / Oil |
50/50 |
Mineral oil - USP |
MONTANIDE ISA 51 VG |
Water / Oil |
50/50 |
Mineral oil - USP |
MONTANIDE ISA 70 VG |
Water / Oil |
30/70 |
Mineral oil - USP |
MONTANIDE ISA 70 M VG |
Water / Oil / Water |
70/30 |
Mineral oil - USP |
MONTANIDE ISA 206 VG |
Water / Oil / Water |
50/50 |
Mineral oil - USP |
MONTANIDE ISA 207 VG |
Water / Oil / Water |
50/50 |
Non Mineral oil - USP |
MONTANIDE ISA 720 VG |
Water / Oil |
30/70 |
Mineral oil - USP |
MONTANIDE IMS
An adjuvant range based on a new concept << ImMunoSol>> and defined as water based non particles associated with an immunostimulating compound.
MONTANIDE
IMS range can be used for sensitive species like Horses/Pets and Fish immersion Vaccines.
CHARACTERISTICS
EASY TO USE
Easy t o Use : Simple mixing of the adjuvant with the antigenic phase. (Magnetic Stirrer)
Easy to Inject : Viscosity of formulations in Less than 5 mPas.
EFFICACIOUS
Efficacious : Induce strong immune response (Short and Long term) along with Humoral and Cellular immunity.
SAFE
Safe : Toxicological tests done demonstrate. Non toxicity and favorable tolerance of IMS Range.
RENDERS
Stable formulation
LEADS to good syringeability
| MONTANIDE IMS RANGE | ||||
|---|---|---|---|---|
Montanide IMS 3011 |
Montanide IMS 1111 |
Montanide IMS 1311 |
Montanide IMS 2211 |
|
Montanide IMS 3012 |
Montanide IMS 1112 |
Montanide IMS 1312 |
Montanide IMS 2212 |
|
Montanide IMS 3013 |
Montanide IMS 1113 |
Montanide IMS 1313 |
Montanide IMS 2213 |
Montanide IMS 1335 |
Montanide IMS 3014 |
Montanide IMS 1114 |
Montanide IMS 1314 |
Montanide IMS 2214 |
Montanide IMS 251 C |
Montanide IMS 3015 |
Montanide IMS 1115 |
Montanide IMS 1315 |
Montanide IMS 2215 |
|
1st Generation |
2nd Generation |
|||
2nd Generation Montanide IMS Range.
- Concentrated Formulation (Increased space for antigen.)
- Improved Stability.
- Excellent Safety Profile (For sensitive species).
- Excellent efficacy
MONTANIDE ADJUVANTS FOR LIVE VACCINES
We offer adjuvant for live vaccines to enable improve protection conferred to vaccinated animals and to reduce antigenic dose of the vaccine.
| MONTANIDE ADJUVANT RANGE | |||
|---|---|---|---|
ADJUVANT |
RATIO |
ADJUVANT TYPE |
TARGET ANIMAL |
Montanide ISA 206 VG |
50% |
Water / Oil / Water |
Pig/Cattle/Poultry |
Montanide ISA 25 VG |
25 to 15% |
Water / Oil |
Pig/Cattle/Poultry |
Montanide ISA 35 VG |
25 to 15% |
Water / Oil |
Pig/Cattle/Poultry |
Montanide IMS 1335 |
25 to 50% |
Nanoparticles |
Pig/Cattle/Poultry |
Montanide IMS 2215 |
15 to 25% |
Water / Oil |
Pig/Pet |
Montanide IMS 251C |
10 to 25% |
Water / Oil |
Pig/Cattle |
Montanide Gel |
10 to 20% |
Aquearesgels |
Pig/Cattle/Poultry |
MONTANIDE GEL
Aqueous Adjuvant based on a Polymeric matrix of synthetic polyacrylic Acid